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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 3
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2002 2
2003 3
2004 3
2005 10
2006 2
2007 4
2008 10
2009 7
2010 10
2011 17
2012 8
2013 7
2014 10
2015 10
2016 14
2017 10
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2020 4
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2022 17
2023 13
2024 8

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184 results

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Page 1
TBX20 Improves Contractility and Mitochondrial Function During Direct Human Cardiac Reprogramming.
Tang Y, Aryal S, Geng X, Zhou X, Fast VG, Zhang J, Lu R, Zhou Y. Tang Y, et al. Circulation. 2022 Nov 15;146(20):1518-1536. doi: 10.1161/CIRCULATIONAHA.122.059713. Epub 2022 Sep 14. Circulation. 2022. PMID: 36102189 Free PMC article.
TBX20 is required for normal heart development and cardiac function in adult cardiomyocytes, yet its role in cardiac reprogramming remains undefined. We show that the addition of TBX20 to the MGT133 cocktail (MGT+TBX20) promotes cardiac reprogramming a …
TBX20 is required for normal heart development and cardiac function in adult cardiomyocytes, yet its role in cardiac reprogram …
The Role of Tbx20 in Cardiovascular Development and Function.
Chen Y, Xiao D, Zhang L, Cai CL, Li BY, Liu Y. Chen Y, et al. Front Cell Dev Biol. 2021 Jan 28;9:638542. doi: 10.3389/fcell.2021.638542. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33585493 Free PMC article. Review.
Mutations in TBX20 are widely associated with the complex spectrum of congenital heart defects (CHDs) in humans, which includes defects in chamber septation, chamber growth, and valvulogenesis. In addition, genetic variants of TBX20 have been found to be asso …
Mutations in TBX20 are widely associated with the complex spectrum of congenital heart defects (CHDs) in humans, which include …
Relationship between TBX20 gene polymorphism and congenital heart disease.
Yang XF, Zhang YF, Zhao CF, Liu MM, Si JP, Fang YF, Xing WW, Wang FL. Yang XF, et al. Genet Mol Res. 2016 Jun 2;15(2). doi: 10.4238/gmr.15027374. Genet Mol Res. 2016. PMID: 27323105 Free article.
Congenital heart disease in children is a type of birth defect. Previous studies have suggested that the transcription factor, TBX20, is involved in the occurrence and development of congenital heart disease in children; however, the specific regulatory mecha …
Congenital heart disease in children is a type of birth defect. Previous studies have suggested that the transcription factor, TBX …
Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion.
Fang Y, Lai KS, She P, Sun J, Tao W, Zhong TP. Fang Y, et al. Front Cell Dev Biol. 2020 Aug 4;8:738. doi: 10.3389/fcell.2020.00738. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32850848 Free PMC article.
Heart regeneration requires replenishment of lost cardiomyocytes (CMs) and cells of the endocardial lining. ...Pharmacologically inactivating endocardial Bmp6 signaling reduces expression of its targets, Id1 and Id2b, attenuating the increased endocardial regeneration in …
Heart regeneration requires replenishment of lost cardiomyocytes (CMs) and cells of the endocardial lining. ...Pharmacologically inac …
Tbx20, Smads, and the atrioventricular canal.
Singh R, Kispert A. Singh R, et al. Trends Cardiovasc Med. 2010 May;20(4):109-14. doi: 10.1016/j.tcm.2010.09.004. Trends Cardiovasc Med. 2010. PMID: 21335279 Review.
Members of the T-box (Tbx) gene family are decisive players in this early myocardial dichotomy by either promoting (Tbx5, Tbx20) or inhibiting (Tbx2, Tbx3) the chamber gene program in the early heart tube. Because Tbx5 and Tbx20 are widely expressed in the li …
Members of the T-box (Tbx) gene family are decisive players in this early myocardial dichotomy by either promoting (Tbx5, Tbx20) or i …
Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis.
Brown DD, Martz SN, Binder O, Goetz SC, Price BM, Smith JC, Conlon FL. Brown DD, et al. Development. 2005 Feb;132(3):553-63. doi: 10.1242/dev.01596. Epub 2005 Jan 5. Development. 2005. PMID: 15634698 Free PMC article.
In this study, we have investigated the cellular and molecular relationship between two T-box genes, Tbx5 and Tbx20. We demonstrate that blocking Tbx5 or Tbx20 produces phenotypes that display a high degree of similarity, as judged by overall gross morphology, molec …
In this study, we have investigated the cellular and molecular relationship between two T-box genes, Tbx5 and Tbx20. We demonstrate t …
The Tbx20-TLE interaction is essential for the maintenance of the second heart field.
Edwards W, Bussey OK, Conlon FL. Edwards W, et al. Development. 2023 Nov 1;150(21):dev201677. doi: 10.1242/dev.201677. Epub 2023 Oct 30. Development. 2023. PMID: 37756602 Free PMC article.
However, a function for the Tbx20-TLE transcriptional repression complex during heart development has yet to be established. We created a mouse model with a two amino acid substitution in the Tbx20 EH1 domain, thereby disrupting the Tbx20-TLE interacti …
However, a function for the Tbx20-TLE transcriptional repression complex during heart development has yet to be established. W …
Tbx20 controls the expression of the KCNH2 gene and of hERG channels.
Caballero R, Utrilla RG, Amorós I, Matamoros M, Pérez-Hernández M, Tinaquero D, Alfayate S, Nieto-Marín P, Guerrero-Serna G, Liu QH, Ramos-Mondragón R, Ponce-Balbuena D, Herron T, Campbell KF, Filgueiras-Rama D, Peinado R, López-Sendón JL, Jalife J, Delpón E, Tamargo J. Caballero R, et al. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E416-E425. doi: 10.1073/pnas.1612383114. Epub 2017 Jan 3. Proc Natl Acad Sci U S A. 2017. PMID: 28049825 Free PMC article.
We functionally analyzed the KCNH2 (encoding for Kv11.1 or hERG channels) and TBX20 (encoding for the transcription factor Tbx20) variants found by next-generation sequencing in two siblings with LQTS in a Spanish family of African ancestry. ...On the contrary, p.R3 …
We functionally analyzed the KCNH2 (encoding for Kv11.1 or hERG channels) and TBX20 (encoding for the transcription factor Tbx20 …
Genetic Variants at the rs4720169 Locus of TBX20 and the rs12921862 Locus of AXIN1 May Increase the Risk of Congenital Heart Defects in the Mexican Population: A Pilot Study.
Hernández-Almaguer MD, Calvo-Anguiano G, Cerda-Flores RM, Salinas-Torres VM, Orozco-Galicia F, Glenn E, García-Guerra J, Sánchez-Cortés G, Lugo-Trampe J, Martínez-Garza LE. Hernández-Almaguer MD, et al. Genet Test Mol Biomarkers. 2019 Sep;23(9):664-670. doi: 10.1089/gtmb.2019.0029. Genet Test Mol Biomarkers. 2019. PMID: 31524541
Background: Congenital heart defects (CHDs) are the most common type of birth defects and a major cause of infant mortality. ...Conclusion: Genetic variants of the TBX20 and AXIN1 genes confer a significantly increased risk of congenital septal heart defects …
Background: Congenital heart defects (CHDs) are the most common type of birth defects and a major cause of infant mortality. ...Concl …
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development.
Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG. Takeuchi JK, et al. Development. 2005 May;132(10):2463-74. doi: 10.1242/dev.01827. Epub 2005 Apr 20. Development. 2005. PMID: 15843409
Complete Tbx20 knockdown resulted in defects in heart formation, including hypoplasia of the outflow tract and right ventricle, which derive from the anterior heart field (AHF), and decreased expression of Nkx2-5 and Mef2c, transcription factors required for …
Complete Tbx20 knockdown resulted in defects in heart formation, including hypoplasia of the outflow tract and right ventricle …
184 results